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January 3, 2013

Discovery News: Jellyfish-Inspired Tentacles Capture Cancer

Source: Discovery News

Original paper: PNAS – Bioinspired multivalent DNA network for capture and release of cells

A new device inspired by jellyfish tentacles can be used to both count and sort cancer cells, which is an important indicator of how well chemotherapy or other treatments are working. Source: Rohit Karnik and Suman Bose

A new device inspired by jellyfish tentacles can be used to both count and sort cancer cells, which is an important indicator of how well chemotherapy or other treatments are working.
Source: Rohit Karnik and Suman Bose

Tiny strands of DNA that float like jellyfish tentacles can grab and hold tumor cells in the bloodstream in a device inspired by nature that may help cancer patients fight the dreaded disease.

The device can be used to both count and sort cancer cells, which is an important indicator of how well chemotherapy or other treatments are working. Doctors need to know whether cancer cells are being knocked out or developing immunity.

“The key is to know which drugs the remaining cells would be most susceptible to,” said Jeffrey Karp, an author on the paper published today in the Proceedings of the Natural Academy of Science (PNAS) and co-director of the Center for Regenerative Therapeutics at Brigham and Women’s Hospital in Boston. “Often these cells in the blood stream are at very low concentrations and it’s difficult to isolate them. What you really want to do is collect them and study the biology of the cells and subject them to different kinds of chemo so you know which one is best to use.”

Read more on Discovery News: Jellyfish-Inspired Tentacles Capture Cancer…

December 11, 2012

MIT News – Inspiration from a porcupine’s quills

Source: MIT News

Inspiration from a porcupine’s quills

Understanding the mechanisms behind quill penetration and extraction could help engineers design better medical devices.

The North American porcupine

The North American porcupine
Photo: Mike Cuccarese

Read more on MIT News – Inspiration from a porcupine’s quills…

December 11, 2012

KarpLab: Finding Inspiration in a Porcupine Quill

December 7, 2012
Laulicht Tape Adhesive Schematic

Medical Tape Innovation Featured On CNN Health

Source: CNN Health – Spiderwebs may inspire better medical tape

Taking medical tape off an adult isn’t too painful because breakage occurs in the glue (you can sometimes see the leftover residue). But removing the same adhesive from a newborn can break fragile skin, causing significant damage, says Jeffrey Karp, researcher at Brigham and Women’s Hospital in Boston.

Traditional medical tape has two layers: the sticky one and the non-sticky one that forms the backing. The adhesive is designed for adults, Karp said; newborns need something else just for them.
Read more on Medical Tape Innovation Featured On CNN Health…